チームリーダー
城口 克之 Ph.D.

Jin J, Ogawa T, Hojo N, et al.
Robotic data acquisition with deep learning enables cell image-based prediction of transcriptomic phenotypes.
Proceedings of the National Academy of Sciences of the United States of America 120(1), e2210283120 (2023) doi: 10.1073/pnas.2210283120

Cui G, Shimba A, Jin J, et al.
A circulating subset of iNKT cells mediates antitumor and antiviral immunity.
Science Immunology 7(76), eabj8760 (2022) doi: 10.1126/sciimmunol.abj8760

Jin J, Yamamoto R, Takeuchi T, et al.
High-throughput identification and quantification of single bacterial cells in the microbiota.
Nature Communications 13, 863 (2022) doi: 10.1038/s41467-022-28426-1

Zhang B, Vogelzang A, Miyajima M, et al.
B cell-derived GABA elicits IL-10⁺ macrophages to limit anti-tumour immunity.
Nature 599(7885), 471-476 (2021) doi: 10.1038/s41586-021-04082-1

Nishida M, Yamashita N, Ogawa T, et al.
Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes.
Journal for immunotherapy of cancer 9, e002954 (2021) doi: 10.1136/jitc-2021-002954

Aso H, Nagaoka S, Kawakami E, et al.
Multiomics investigation revealing the characteristics 1 of HIV-1-infected cells.
Cell Reports 32, 107887 (2020)

Kimura S, Nakamura Y, Kobayashi N, et al.
Osteoprotegerin-dependent M cell self-regulation balances gut infection and immunity.
Nature Communications 11, 234 (2020) doi: 10.1038/s41467-019-13883-y

Yazaki J, Kawashima Y, Ogawa T, et al.
HaloTag-based conjugation of proteins to barcoding-oligonucleotides.
Nucleic Acids Research 48, e8 (2020) doi: 10.1093/nar/gkz1086

Miyamoto C, Kojo S, Yamashita M, et al.
Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation.
Nature Communications 10, 447 (2019) doi: 10.1038/s41467-019-08365-0

Ise W, Fujii K, Shiroguchi K, et al.
T follicular helper cell-germinal center B cell interaction strength regulates entry into plasma cell or recycling GC cell fate.
Immunity 48, 702-715 (2018) doi: 10.1016/j.immuni.2018.03.027

Tenno M, Kojo S, Lawir DF, et al.
Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors.
Journal of Experimental Medicine 215, 595-610 (2018) doi: 10.1084/jem.20171221

Ogawa T*, Kryukov K*, Imanishi T, Shiroguchi K.
The efficacy and further functional advantages of random-base molecular barcodes for absolute and digital quantification of nucleic acid molecules.
Scientific Reports 7, 13576 (2017) doi: 10.1038/s41598-017-13529-3

Tenno M, Shiroguchi K, Muroi S, et al.
Cbfβ2-deficiency preserves Langerhans cell precursors by lack of selective TGFβ receptor signaling.
Journal of Experimental Medicine 214(10), 2933-2946 (2017) doi: 10.1084/jem.20170729

Suzuki H, Mitsuno K, Shiroguchi K, et al.
One-step micromolding of complex 3D microchambers for single-cell analysis.
Lab on a Chip 17(4), 647-652 (2017) doi: 10.1039/c6lc01313a

Chen HY*, Shiroguchi K*, Ge H, Xie XS.
Genome-wide study of mRNA degradation and transcript elongation in Escherichia coli.
Molecular Systems Biology 11(1), 781 (2015) doi: 10.15252/msb.20145794

Miyazaki M, Kinosita K, Shiroguchi K.
Accurate polarity control and parallel alignment of actin filaments for myosin-powered transport systems.
Rsc Advances 3(23), 8728-8733 (2013) doi: 10.1039/c3ra41112e

Shiroguchi K, Jia TZ, Sims PA, Xie XS.
Digital RNA sequencing minimizes sequence-dependent bias and amplification noise with optimized single-molecule barcodes.
Proceedings of the National Academy of Sciences of the United States of America 109(4), 1347-1352 (2012) doi: 10.1073/pnas.1118018109

Shiroguchi K, Chin HF, Hannemann DE, et al.
Direct Observation of the Myosin Va Recovery Stroke That Contributes to Unidirectional Stepping along Actin.
PLOS Biology 9(4), e1001031 (2011) doi: 10.1371/journal.pbio.1001031

Shiroguchi K, Kinosita K.
Myosin V walks by lever action and Brownian motion.
Science 316(5828), 1208-1212 (2007) doi: 10.1126/science.1140468