Team Leader
Shigeru Kuratani Ph.D.

Laboratory for Evolutionary Morphology

[Closed Mar. 2024]

E-mailshigeru.kuratani[at]riken.jp

Please replace [at] with @.

Overview
Selected Publications
News

What’s New

Jan. 29, 2024 BDR News

BDR Scientist Shigeru Kuratani Awarded The Asahi Prize

Evo-Devo studies to understand the origin of evolutionary novelties in vertebrates

Evolution can be viewed as series of changes introduced to developmental programs of organisms. The ultimate goal of our research project is to reconstruct the mechanical background of development behind evolutionary novelties in vertebrates, such as jaws and turtle crapace, by comparing developmental processes and patterns between different animal species to identify the changed portion of development, by constructing phenocopies to modify a part of developmental programs of model animals, and by integrating the experimental data with fossil data, phylogenetic trees based on molecular data, and variety of genomes in animals.

Research Theme

Head
Skeletomuscular system
Nervous system
Vertebrates
Cyclostomes

Selected Publications

Hirasawa T, Hu Y, Uesugi K, et al.
Morphology of Palaeospondylus shows affinity to tetrapod ancestors.
Nature 606(7912), 109-112 Wed Jun 01 00:00:00 JST 2022 doi: 10.1038/s41586-022-04781-3

Takagi W, Sugahara F, Higuchi S, et al.
Thyroid and endostyle development in cyclostomes provides new insights into the evolutionary history of vertebrates.
BMC Biology 20(1), 76 Fri Apr 01 00:00:00 JST 2022 doi: 10.1186/s12915-022-01282-7

Higuchi S, Sugahara F, Pascual-Anaya J, et al.
Inner ear development in cyclostomes and evolution of the vertebrate semicircular canals.
Nature 565(7739), 347-350 Tue Jan 01 00:00:00 JST 2019 doi: 10.1038/s41586-018-0782-y

Pascual-Anaya J, Sato I, Sugahara F, et al.
Hagfish and lamprey Hox genes reveal conservation of temporal colinearity in vertebrates.
Nature Ecology & Evolution 2(5), 859-866 Sat Dec 01 00:00:00 JST 2018 doi: 10.1038/s41559-018-0526-2

Sugahara F, Pascual-Anaya J, Oisi Y, et al.
Evidence from cyclostomes for complex regionalization of the ancestral vertebrate brain.
Nature 531, 97-100 Thu Dec 01 00:00:00 JST 2016 doi: 10.1038/nature16518

Wang Z, Pascual-Anaya J, Zadissa A, et al.
Development and evolution of turtle-specific body plan assessed by genome-wide analyses.
Nature Genetics 45, 701-706 Sun Dec 01 00:00:00 JST 2013 doi: 10.1038/ng.2615

Oisi Y, Ota KG, Kuraku S, et al.
Craniofacial development of hagfishes and the evolution of vertebrates.
Nature 493, 175-180 Tue Oct 01 00:00:00 JST 2013 doi: 10.1038/nature11794

Nagashima H, Sugahara F, Takechi M, et al.
Evolution of the turtle body plan by the folding and creation of new muscle connections.
Science 325, 193-196 Tue Dec 01 00:00:00 JST 2009 doi: 10.1126/science.1173826

Ota KG, Kuraku, S, Kuratani S.
Hagfish embryology with reference to the evolution of the neural crest.
Nature 446, 672-675 Sat Dec 01 00:00:00 JST 2007 doi: 10.1038/nature05633

Takio Y, Pasqualetti M, Kuraku S, et al.
Evolutionary biology: lamprey Hox genes and the evolution of jaws.
Nature 429(6989), 622 Thu May 20 00:00:00 JST 2004 doi: 10.1038/nature02616

Shigetani Y, Sugahara F, Kawakami Y, et al.
Heterotopic shift of epithelial-mesenchymal interactions in vertebrate jaw evolution.
Science 296(5571), 1316-1319 Fri May 17 00:00:00 JST 2002 doi: 10.1126/science.1068310