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Research

Research

BDR researchers coming from diverse research fields are working together to achieve higher goals.

Seminars & Symposia

Seminars & Symposia

BDR hosts annual symposium and regular seminars inviting international scientists in life science.

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Careers & Study

BDR embraces people from diverse backgrounds, and strives to create an open and supportive setting for research.

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Outreach

BDR communicates the appeal and significance of our research to society through the use of various media and activities.

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News

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About Us

About Us

Exploring the scientific foundations of life through interdisciplinary approaches to address society’s problems.

Photo of Team leder, Toshio Yamazaki

Unit Leader
Toshio Yamazaki Ph.D.

Laboratory for NMR Engineering and Structural Science

LocationYokohama / West NMR building

E-mailtoshio.yamazaki[at]riken.jp

Please replace [at] with @.

We are developing experimental technologies and instruments for nuclear magnetic resonance (NMR) spectroscopy. Ultra-high magnetic fields produced by high-temperature superconductors leads to higher NMR sensitivity and resolution. We are working to enhance the performance of the spectrometer to accommodate higher magnetic fields and frequencies. A higher magnetic field will yield more advantages. We will develop new techniques for detecting the structure and movements of molecules as well as develop new types of magnets and detection probes enabling analyses of wider range of samples and conditions.

Research Theme

  • Nuclear magnetic resonance
  • photoisomerization
  • High-temperature superconductivity
  • Protein folding

Selected Publications

Wu N, Kobayashi N, Tsuda K, et al.
Solution structure of Gaussia Luciferase with five disulfide bonds and identification of a putative coelenterazine binding cavity by heteronuclear NMR.
Scientific Reports 10, 20069 (2020)

Ohyama T, Takahashi H, Sharma H, et al.
An NMR-based approach reveals the core structure of the functional domain of SINEUP lncRNAs.
Nucleic Acids Research 48, 9346-9360 (2020)

Guzmán-Afonso C, Hong YL, Colaux H, et al.
Understanding hydrogen-bonding structures of molecular crystals via electron and NMR nanocrystallography.
Nature Communications 10(1), 3537 (2019)

Nagashima T, Ueda K, Nishimura C, Yamazaki T.
Structure-Correlation NMR Spectroscopy for Macromolecules Using Repeated Bidirectional Photoisomerization of Azobenzene.
Analytical Chemistry 87, 11544-52 (2015)

Hashi K, et al.
Achievement of 1020 MHz NMR.
Journal of Magnetic Resonance 256, 30-33 (2015)

Members

Toshio Yamazaki

Unit Leader

Takashi Nakamura

Senior Technical Scientist

Masato Takahashi

Senior Scientist

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