Team Leader
Shunsuke Tagami Ph.D.

Yagi S, Tagami S.
An ancestral fold reveals the evolutionary link between RNA polymerase and ribosomal proteins
Nature Communications (2024) doi: 10.1038/s41467-024-50013-9

Chaban A, Minakhin L, Goldobina E, et al.
Tail-tape-fused virion and non-virion RNA polymerases of a thermophilic virus with an extremely long tail
Nature Communications (2024) doi: 10.1038/s41467-023-44630-z

Mohri K, Huynh Nhat KP, Zouda M, et al.
Lasso peptide microcin J25 variant containing RGD motif as a PET probe for integrin αvβ3 in tumor imaging
European Journal of Pharmaceutical Sciences (2022) doi: 10.1016/j.ejps.2022.106339

Alfi A, Popov A, Kumar A, et al.
Cell-Free Mutant Analysis Combined with Structure Prediction of a Lasso Peptide Biosynthetic Protease B2
ACS Synthetic Biology (2022) doi: 10.1021/acssynbio.2c00176

Li P, Holliger P, Tagami S.
Hydrophobic-cationic peptides modulate RNA polymerase ribozyme activity by accretion
Nature Communications 13, 3050 (2022) doi: 10.1038/s41467-022-30590-3

Yagi S, Padhi AK, Vucinic J, et al.
Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase.
Journal of the American Chemical Society (2021) doi: 10.1021/jacs.1c05367

Sumida T, Dubiley S, Wilcox B, et al.
Structural Basis of Leader Peptide Recognition in Lasso Peptide Biosynthesis Pathway.
ACS Chemical Biology., 14(7), 1619-1627 (2019) doi: 10.1021/acschembio.9b00348

Tagami S, Attwater J, Holliger P.
Simple peptides derived from the ribosomal core potentiate RNA polymerase ribozyme function.
Nature Chemistry 9, 325-332 (2017) doi: 10.1038/nchem.2739

Tagami S, Sekine S, Minakhin L, et al.
Structural basis for promoter specificity switching of RNA polymerase by a phage factor.
Genes & Development 28(5), 521-531 (2014) doi: 10.1101/gad.233916.113

Tagami S, Sekine S, Kumarevel T, et al.
Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor protein.
Nature 468(7326), 978-982 (2010) doi: 10.1038/nature09573