logomark
Research

Research

BDR researchers coming from diverse research fields are working together to achieve higher goals.

Seminars & Symposia

Seminars & Symposia

BDR hosts annual symposium and regular seminars inviting international scientists in life science.

Careers & Study

Careers & Study

BDR embraces people from diverse backgrounds, and strives to create an open and supportive setting for research.

Outreach

Outreach

BDR communicates the appeal and significance of our research to society through the use of various media and activities.

News

News

From research, events, people and everything in between, find out what’s going on at RIKEN BDR.

About Us

About Us

Exploring the scientific foundations of life through interdisciplinary approaches to address society’s problems.

Photo of Team leder, Shunsuke Tagami

Team Leader
Shunsuke Tagami Ph.D.

Laboratory for Advanced Biomolecular Engineering

LocationYokohama

E-mailshunsuke.tagami[at]riken.jp

Please replace [at] with @.

We are developing biomacromolecules that control enzymes and cells

Research Theme

  • We are engineering peptides that control cells and enzymes for use in medical and basic science.
  • We are trying to experimentally reconstruct evolutional pathway from primordial peptides to elaborate proteins.

Selected Publications

Yagi S, Padhi AK, Vucinic J, et al.
Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase.
Journal of the American Chemical Society (2021) doi: 10.1021/jacs.1c05367

Li P, Holliger P, Tagami S.
Hydrophobic-cationic peptides enhance RNA polymerase ribozyme activity by accretion.
bioRxiv (2021) doi: 10.1101/2021.02.22.432394

Sumida T, Dubiley S, Wilcox B, et al.
Structural Basis of Leader Peptide Recognition in Lasso Peptide Biosynthesis Pathway.
ACS Chemical Biology., 14(7), 1619-1627 (2019) doi: 10.1021/acschembio.9b00348

Tagami S, Attwater J, Holliger P.
Simple peptides derived from the ribosomal core potentiate RNA polymerase ribozyme function.
Nature Chemistry 9, 325-332 (2017) doi: 10.1038/nchem.2739

Tagami S, Sekine S, Minakhin L, et al.
Structural basis for promoter specificity switching of RNA polymerase by a phage factor.
Genes & Development 28(5), 521-531 (2014) doi: 10.1101/gad.233916.113

Tagami S, Sekine S, Kumarevel T, et al.
Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor protein.
Nature 468(7326), 978-982 (2010) doi: 10.1038/nature09573

Members

Photo of Team leder, Shunsuke Tagami

Team LeaderShunsuke Tagami

member photo

Research ScientistPeiying Li

  • peiying.li[at]riken.jp
  • CV
member photo

Special Postdoctoral ResearcherSota Yagi

  • sota.yagi[at]riken.jp
  • CV
member photo

Research ScientistAlmasul Alfi

  • almasul.alfi[at]riken.jp
  • CV

AssistantTami Kosuge

  • tami.kosuge[at]riken.jp

(Please replace [at] with @)

PAGE
TOP