Team Leader
Shunsuke Tagami
Ph.D.
Laboratory for Advanced Biomolecular Engineering
LocationYokohama
E-mailshunsuke.tagami[at]riken.jp
Please replace [at] with @.
Research Theme
- We are engineering peptides that control cells and enzymes for use in medical and basic science.
- We are trying to experimentally reconstruct evolutional pathway from primordial peptides to elaborate proteins.
Selected Publications
Yagi S, Padhi AK, Vucinic J, et al.
Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase.
Journal of the American Chemical Society
(2021)
doi: 10.1021/jacs.1c05367
Li P, Holliger P, Tagami S.
Hydrophobic-cationic peptides enhance RNA polymerase ribozyme activity by accretion.
bioRxiv
(2021)
doi: 10.1101/2021.02.22.432394
Sumida T, Dubiley S, Wilcox B, et al.
Structural Basis of Leader Peptide Recognition in Lasso Peptide Biosynthesis Pathway.
ACS Chemical Biology.,
14(7), 1619-1627 (2019)
doi: 10.1021/acschembio.9b00348
Tagami S, Attwater J, Holliger P.
Simple peptides derived from the ribosomal core potentiate RNA polymerase ribozyme function.
Nature Chemistry
9, 325-332 (2017)
doi: 10.1038/nchem.2739
Tagami S, Sekine S, Minakhin L, et al.
Structural basis for promoter specificity switching of RNA polymerase by a phage factor.
Genes & Development
28(5), 521-531 (2014)
doi: 10.1101/gad.233916.113
Tagami S, Sekine S, Kumarevel T, et al.
Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor protein.
Nature
468(7326), 978-982 (2010)
doi: 10.1038/nature09573
Members
Team LeaderShunsuke Tagami
- shunsuke.tagami[at]riken.jp
(Please replace [at] with @) - CV [PDF size：102KB]
