1. State of the art in biomedical image denoising 2. Super-resolution methods for blinking fluorescence imaging
Oct. 21, 2019 13:00 - 14:30

Seminar

Osaka

Osaka Lounge A1F TVconference Kobe S104 C1F

1. Andrey Krylov 2. Yakov Pchelintsev

Faculty of Computational Mathematics and Cybernetics, Lomonosov Moscow State University

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1. Convolutional neural networks (CNN)show very good performance and achieve impressive results in biomedical image denoising.Nevertheless CNN-based methods strongly depend on the used training set and even small differences in the input data can cause output disturbance.Thus new more reliable hybrid denoising methods were suggested.They include combinations of CNN and «classical»algorithms like Non-Local Means,BM3D,Bilateral,Anisotropic diffusion,Total Variation(TV),etc.However hybrid methods need non-reference automatic parameters estimation for classical algorithms.In this papaer we presenta a hybrid DnCNN+BM3D method with automatic choice of the strength parameter for BM3D method.To contorol biomedical image structures by multiscale ridge difference between noisy and filtered images.Test results for different image datasets show practical applicability of the method. Some possible applications of he hybrid methods for blinking fluorescene imaging enhancement will be presented.


2. A probabilistic approach for super-resolution of blinking fluorescence microscopy will be presented.Its performance will be compared with modern blinking fluorescence image enhancement alorithms,namely SOFI,MUSICAL and SPARCOM in different conditions.The comparison will be performed usin both synthetic and real experimental data.The possible future work on blinking fluorescence imaging enhancement will be discussed.

Yasushi Okada